Grapefruit is a longtime marijuana classic, a heady blend of the hybrid Cinderella 99 and a Sativa bred specifically for its grapefruit flavor. With a sativa/indica ratio of about 70:30, this strain packs a decidedly cerebral punch, with a major mood boost and intense euphoria. But it’s highly effective at relieving anxiety and depression, as well as pain, GI distress, and PMS. The sweet taste and smell of grapefruit are dominant, thought there are also hints of other citrus fruits. Adverse effects are usually quite limited, though dry mouth and red eyes are possible. Dizziness and paranoia are more rare. Grapefruit is common across the country, sold largely on the basis of its unique flavor and aroma. It’s most popular in Colorado and on the West Coast, though it can also be found in other legal markets and the black market. This strain is highly appealing to smokers looking for a strong head high, less so to patients seeking physical effects.